An Efficient Synthesis of Carborane Amines via One-Step Reaction of Carborane Triflates with N-Nucleophiles

Olshevskaya V.A., Dutikova Y.V., Tyutyunov A.A., Kononova E.G., Petrovskii P.V., Kalinin V.N., Sung D.D.

1-Trifluoromethanesulfonylmethyl-o-carborane and cesium 1-trifluoromethanesulfonylmethyl-1-carba-closo-dodecaborate react with amines in refluxing acetonitrile in the presence of NaOAc without a catalyst to give the corresponding amino derivatives. This approach allows for simple synthesis of neutral and anionic carborane amines not readily available via other synthetic routes.